Postretinal Structure and Function in Severe Congenital Photoreceptor Blindness Caused by Mutations in the GUCY2D Gene.
Aguirre GK, Butt OH, Datta R, Roman AJ, Sumaroka A, Schwartz SB, Cideciyan AV, Jacobson SG.
Aguirre GK, et al.
Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):959-973. doi: 10.1167/iovs.16-20413.
Invest Ophthalmol Vis Sci. 2017.
PMID: 28403437
Free PMC article.
RESULTS: Patients with GUCY2D-LCA had preservation of the photoreceptors, ganglion cells, and nerve fiber layer. Despite this, visual function in these patients ranged from 20/160 acuity to no light perception, and functional MRI responses to light stimulation were attenua …
RESULTS: Patients with GUCY2D-LCA had preservation of the photoreceptors, ganglion cells, and nerve fiber layer. Despite this, visual …